Agodox 100mg Capsule contains doxycycline, a tetracycline antibiotic. It is widely prescribed in Tanzania for respiratory tract infections, some sexually transmitted infections, malaria prophylaxis, and acne.
Available Product Formulations
Capsule: doxycycline hyclate 100 mg.
Uses
Respiratory infections, chlamydia, rickettsial infections, malaria prophylaxis (travel or endemic regions), and moderate to severe acne.
How to Use
- Dosage: Adults: 100 mg once or twice daily. Malaria prophylaxis: 100 mg daily starting 1–2 days before travel, continued during stay and 4 weeks after leaving endemic area.
- Duration: Depends on infection type (usually 7–14 days for infections).
Side Effects
Photosensitivity (sunburn risk), nausea, vomiting, diarrhea, esophageal irritation if taken without water. Rarely, intracranial hypertension.
Interactions
Reduced absorption with dairy, antacids, or iron. May reduce effectiveness of oral contraceptives. Interacts with anticoagulants and retinoids.
Warnings
Avoid in children under 8 years and in pregnancy. Take with full glass of water, remain upright for 30 minutes. Use sunscreen due to photosensitivity risk.
Summary of Important Information
| Active Ingredients |
Doxycycline 100 mg |
| Dosage Frequency |
Once or twice daily |
| Starting Time |
Start after prescription; malaria prophylaxis begins 1–2 days before travel |
| Duration of Use |
7–14 days for infections; varies for malaria prophylaxis |
| Common Side Effects |
Nausea, diarrhea, photosensitivity |
| Warnings |
Not for children <8 years; pregnancy caution; stay upright after dose |
How Agodox 100mg Capsule Works
Doxycycline binds to the 30S ribosomal subunit, preventing bacterial protein synthesis and inhibiting growth.